We Offer

Florentis offers services in custom synthesis, asymmetric synthesis, process development, purification by novel techniques, analytical services and reference standards of drug intermediates, APIs, impurities and metabolites.

Synthetic & Medicinal Chemistry

We design and synthesize diverse structural classes of organic molecules from mg to kg scale. We are well equipped to carry out multi-step organic synthesis of varied complexity.

• Synthesis of Libraries of compounds.
• Synthesis of Scaffolds for NCEs.
• Synthesis of building blocks.
• Solid phase organic synthesis.

Asymmetric synthesis

Florentis has an extensive expertise in asymmetric synthesis and utilizes approaches like chiral pool, asymmetric catalysis including metal as well as organocatalysis, chiral resolution, etc.

• Synthesis of chiral building blocks.
• Synthesis of chiral drug intermediates and APIs.
• Design and development of chiral ligands.

Purification by Novel Techniques

Florentis has developed novel techniques for the purification of organic compounds from mg to kg scale.

• Water soluble and acid sensitive compounds.
• Highly polar compounds such as sulphonamides, urea, guanidinium and other salts.

Process Development

We also work for our clients in the field of process development, validation as well as technical support to scale-up operations.

• Route of synthesis- optimization and validation
• Procurement of raw materials
• Scale up from lab to kilo lab

Analytical Services

We provide following analytical services:

• HPLC analysis (Chiral and reverse phase)
• ee determination
• Structure elucidation
• Preparative column chromatography
• LCMS and ¹H NMR (Collaborator’s facility)